The biblical Isaac was the only son of Abraham by his wife Sarah. The prediction of his birth was amusing to the couple because they were very old, so God gave them the name Isaac for their son, meaning one who laughs. And who doesn't want a cheerful baby? Isaac is very popular today like many other retro-chic names that are coming back in vogue.
Physicist Sir Isaac Newton, Author Isaac Asimov, Designer Isaac Mizrahi, Musician Isaac Hanson
Son of Joel McHale, Son of Mandy Patinkin, Son of Annie Potts