Q&A: What day of my cycle do I take Clomiphene?

by Dr. Gerard M. DiLeo

I am 40 and have been trying to conceive for the last four years. I have two children already. I have had a thorough check-up and blood tests to determine that I am still ovulating. My husband's sperm has been checked and is fine. I have been prescribed Clomiphene 50 mg. to be taken on days five through nine of my cycle.

I started the Clomiphene as prescribed on my last cycle, which consisted of five days of spotting. After I started the medication, I bled heavily for five days more. I went six days and then started spotting lightly again.

Because my cycle has been so abnormal, I am unsure which day to count as day five to begin the Clomiphene again.

Since your first regimen of Clomiphene resulted in a "mess" of sorts, you're going to have to stop taking it and allow yourself to re-start normal cycling to get the timing right. If you're ovulating with a good progesterone level at day 21 or so, you probably don't need the Clomiphene. If your progesterone levels are low after ovulation, then Clomid can help. Also, there's an increase in the dose each cycle if the previous cycle doesn't result in a normal ovulation with a good post-ovulation progesterone level.

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