Fertility Medications: Common Questions Answered

by Dr. Richard H. Reindollar

Human Chorionic Gonadotropin or hCG: (Novarel, Ovidrel, Pregnyl) is a hormone that matures the developing follicles and triggers release of an egg from its follicle. This drug is given once at the end of the treatment cycle (usually seven to 10 days), two days before the intrauterine insemination is performed. Administration is injection under the skin, with one form now available in pre-filled syringes.

Success Rates

Success rates for ovulation induction and IUI will vary depending on the specific circumstances of each case, however the average population success rates for ovulation induction and IUI treatment options reported in the medical literature are shown below.

Success Rate (per cycle)

  • Non-medicated IUI: 4 percent
  • Clomiphene citrate, no IUI: 6 percent
  • Clomiphene citrate-IUI: 8-10 percent
  • FSH, no IUI: 10 percent
  • FSH-IUI: 15-18 percent
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