The FDA has dictated a code of federal registry that delineates five categories of the relative safety of drugs when used during pregnancy. (Section 201.57 of the federal drug registry.) Pregnancy Class D means that abnormal findings have been found in animal studies, and there has been positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans. However, the potential benefits from the use of the drug may be acceptable despite its potential risk. These drugs, such as aspirin, the anticonvulsant Deproic and the antidepressant Depromin, are most commonly used during a life-threatening situation when safer drugs cannot be used.
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