Danazol is the generic name of a synthetic hormone; the commercial trade name commonly used is Danocrine. It is used to treat pain and infertility caused by endometriosis, a condition involving the tissue of the uterus. It is also used in the treatment of cysts or lumps in the breast or may be prescribed for heavy menstrual flow. In the treatment of endometriosis, Danazol alters the endometrial tissue both within and outside the uterus so that it becomes inactive and atrophic. Complete resolution of endometrial lesions occurs in the majority of cases. Generally, the pituitary-suppressive action of Danazol is reversible. Ovulation and cyclic bleeding usually return within 60 to 90 days when therapy with Danazol is discontinued. Danazol should not be used while pregnant.
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