There are three different vaccine products (HbOC, also called HibTITER; PRP-OMP, also referred to as PedvaxHIB or Comvax; and PRP-T, also called ActHIB or OmniHib) to fight Hib on the market. Doses are needed at two and four months. A dose at six months is necessary if HbOC or PRP-T is used, but not with PRP-OMP. A final dose after 12 months of age is necessary for all. The Hib vaccine has markedly reduced the occurrence of serious and fatal Hib infections.