A large, zinc-binding protein that acts as an enzyme, specifically a metallopeptidase (the gene for PAPPA is in chromosome band 9q33.1). PAPPA has been used in prenatal genetic screening and studies of atherosclerosis. Women with low blood levels of PAPPA at pregnancy weeks eight to 14 weeks have an increased risk of intrauterine growth restriction, trisomy 21, premature delivery, preeclampsia, and stillbirth.
Can You Sleep Your Way to Conception?
Expert Q & A
The TTC Community
Sing, Sing a Song?
Real Mom Tips
Celebrity Parenting
Your Baby Book
1st Birthday Recipes
Baby Shower Fun
Good Toddler Apps
Gifts for Newborns
Baby Slings
Snooki Says...
Work-Life Balance
WAHM