|
Demerol Meperidine hydrochloride (Demerol), either alone or in combination with promethazine hydrochloride (Phenergan), has the advantage of a history of extensive use in labor. Common dosing is 50 to 100 mg of meperidine and 25 to 50 mg of promethazine IM every 3 to 4 hours. Both medications can be given IV, but at reduced dosages of 25 to 50 mg of meperidine (diluted to 10 mg/mL) and 25 mg of promethazine. Since metabolic by-products of meperidine may have half-lives of 8 to 21 hours and will accumulate in patients with renal impairment and in their premature fetuses and neonates, the risk-benefit ratio requires re-evaluation before repeated dosing. The manufacturers recommend giving no more than 100 mg of promethazine during 24 hours of labor. |
Free BabyZone Tools
Get Full Access Now!
- Personalized Calendars & Weekly Emails
- Interactive Tools & Resources
- FREE Stuff & Special Deals
Free Stuff Picks
Great Deals & Free Stuff
Get discounts on baby formula, win FREE diapers and more. Check out these amazing offers now!
Take me to BabyZone Free Stuff
